What must teachers be aware of about brain-based learning when teaching online courses?

When looking at brain-based learning in online education I think that teachers need to look at relating the content that they teach to the  student's experiences. They need to assign assignments that make connections and  look at relating topics to real world problems. Because online teachers can't physically interact with their students, sometimes they need to be more focused on the student and their needs.
Teachers also need to to help create an online learning community within the class where students feel comfortable to share their views and ideas.